This may be the biggest TV inception we’ve ever heard of!

Charmed’s OG Halliwell sisters are reuniting (well, two of them!) – they’re set to appear on Grey’s Anatomy.

Alyssa Milano and Holly Marie Combs (Phoebe and Piper) will play sisters once again, in a special episode of Grey’s Anatomy which is set to air on October 10.

People reports that the sisters’ characters decide whether or not to take heir third sister off life support after being left ‘brain’ dead’ by a construction site accident.

The TV inception is part of American ABC’s “Cast From The Past Week’” where various cast members and creative teams will reunite in new episodes of ABC shows.

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John Goodman is being joined by fellow Blue Brothers star Dan Aykroyd for an episode of The Conners.

And Ken Jeong will also be reunited with Crazy Rich Asians star Constance Wu when he returns to Fresh Off the Boat.

We.Can’t.Even.

Love this? You’ll love this bit from Kyle & Jackie O!